This is formed in the myeloid tissues or
more commonly known as red bone marrow, although when the body is under severe
conditions the yellow bone marrow which is also the fatty places of trhe
marrow in the body will also make Red
Blood Cells (RBCs). The production cell is called erythropoiesis. RBCs loses
nuclei upon maruration and take on biconcave, dimpled shape. They are about 7-8
um in diameter ha having a liter which contains 5x10 12 of RBS
(Cheesbrough,
2000).
The production of the red blood cells is in the bone marrow, this is
possible whenever there is tissue hypoxia (clack of oxygen) leading to the
release of the hormones known as erythropoietin which stimulates progenior
cells BFU-E and CFU-E to develop into pronormoblasts proerythroblasts). This
process takes about 3-5 days (Chessbrough; 2000). A the globin is the protein
which is about 250 million/cell. the globin is the protein substances of four
different protein: polypeptide globin chains that contain 141-146 amito acids
and is also responsible for the cell’s moiety of haemoglobin to which the iron
is bound (Boh; 2001).
This
is the iron carrying capacity of the red
blood cell; also it can be said to be the oxygen-transport of metallo-protein
in the red blood cells of all verterbrates (Maton et al; 1993). Haemoglobin
helps in the carrying of blood oxygen from the et al; 1981). This increases the
total blood oxygen capacity seventy-fold compared to dissolved oxygen in the
blood. It is measured to detect anaemia
and its severity which aids to monitor an anaemic patient’s response to
treatment (Cheesbrough; 200). The haemoglobin is a group of globular protein
subunit and is composed of a protein chain tightly associated with a
non-protein heme group.
Normal
ranges:
5.0-120
x 109/L Red Blood Cells.
130-180g/dl
haemolobin (Cheesbrough, 2000).
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