METHODS OF ANALYSIS WITH REFERENCE NUMBER



Samples were analyzed chemically according to the official methods of analysis described by the Association of Analytical Chemist (AOAC. 18th edition, 2005). All analysis were:
 
CRUDE PROTEIN DETERMINATION (AOAC OFFICIAL METHOD 988.05)
The crude protein in the samples were determined by the routine semi micro Kjeldahl, procedure/technique. This consists of three techniques of analysis namely digestion, distillation and titration.
APPARATUS: Analysis Balance, Digestion tubes, Digestion Block Heaters, 50ml Burette, 5ml Pipette, 10ml measuring Cylinder, 100ml Beakers, Fume Cupboard.

REAGENTS: Conc. H2SO4, 0.01NHCL, 40% (W/V) NaOH, 2% Boric Acid Solution, Methyl Red Bromocresol green mixed indicator, Kjeldahl Catalyst tablet.
DIGESTION
           0.5g of each finely ground sample was weighed carefully in the Kjeldahl digestion tubes to ensure that all sample materials got to the bottom of the tubes. To this were added 1 Kjeldahl catalyst tablet and 10ml of Conc. H2SO4. These were set in the appropriate hole of the Digestion blocks Heaters in a fume cupboard. The Digestion was left for 4 hours, after which a clear colorless solution was left in the tubes. The digest was cooled and carefully transferred into 100ml volumetric flask, thoroughly rising the digestion tube will distilled water and the flask was made up to mark the distilled water.
DISTILLATION
         The distillation was done with Markham Distillation Apparatus which allow volatile substances such as ammonia to be steam distilled with complete collection of the distillate. The apparatus was steamed out for about ten minutes. The steam generator is then removed from the heat source to all the developing vacuum to removed condensed water. The steam generator was placed on the heat source (i.e. Heating mantle) and each component of the apparatus was fixed up appropriately.
Determination : 5ml portion of the digest above was pipette into the body of the apparatus via the small funnel aperture. To this was added 5ml of 40% (W/V) NaOH through the same opening with 5ml pipette.
              The mixture was steam distilled for 2 minutes into a 5ml conical flask containing 10ml of 2% Boric Acid plus mixed indicator solution placed at the receiving up of the condenser. The Boric Acid plus the indicator solution changes color from red to green showing that all the ammonia liberated have been trapped.

TITRATION
       The green colored solution obtained was then titrated against 0.01N HCL contained in a 50ml Burette. At the end point or the equivalent point the green color turns to wine color which indicator that all the nitrogen trapped as Ammonia Borate [(NH4)2BO3)] have been removed as
Ammonia chloride (NH4CL).
      The percentage nitrogen in this analysis was calculated using the formula:
       %N = Titre value x Atomic mass of nitrogen x Normality of HCL used x 4
        Or %N = Titre value x Normality/Morality of HCL used x Atomic mass of
          N x Volume of flask containing the digest x 100
     Weight of sample digested in milligram x Vol. of digest for steam distillation. The crude protein content was determined by multiplying percentage Nitrogen by a constant factor of 6.25 i.e. % CP= %N x 6.25.
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