PHYSICOCHEMICAL STUDIES OF EXTRACTS FROM NABOLEONA VOGELLI HOOK GROWN AS A SOURCE OF NEW ACID-BASE INDICATOR



Abstract
Physico-chemical studies of the extracts from Napoleona Vogelli as an alternative source of new acid-base indicators derived from locally available plants were investigated.  Three solvents phases (organic, organic/aqueous (50:50) and aqueous) were employed in the extraction process.
The organic phase extract was readily purified and was used for further investigation. Thin layer chromatography (TLC) separation of this extract yielded six components, acid-base, titration of the organic phase extract produced results quit comparable with phenolphthalein and methyl orange using 0.01m and 0.10m Na0H and HCL respectively. All the extract and components were also titrated under similar conditions and proved suitable as indicators for acid base titrimetry, involving strong acid versus strong base, strong acid versus weak base, as well as weak acid versus weak base. They were not suitable for weak acid versus strong base. The calculated PK a value of 9.8 of the organic extract compound with 9.60 of phenolphthalein confirms the extract as a weak acid. These values suggest that Napoleona vogelli extracts are a suitable alternative source of acid-base indicators from local plants.

CHAPTER ONE
INTRODUCTION
            In Ebonyi state, many interesting plants abounds with rich cultural value and hence demands scientific investigation. The studies of their physiochemical properties are important because people living around the areas uses the plants as direct foods and supplements, herbal medicines, ornamentals, and agro-chemicals. The physicochemical studies of substances involve identification and/or characterization based on their physical and chemical properties (Solan and Sirry, 2002). Physical properties do not lead to changes in chemical identity (Soltan and Sirry, 2002) and (Gruden, 2000) whereas chemical properties can result to alternation in chemical identities such as pH, toxicity, flammability, colour changes, reactivity with water, etc (Musoke, 2002), (Geotge et al. 1987) and, (Ekandem and Owor, 1997). An acid-base indicator may be used to indicate the endpoint of a particular neutralization reaction, or the ph of a system (Gruden, 2000), and (Geroge et al., 1987).
            Many substances, both naturally occurring and synthetic, display colours that depend on the pH of the solutions in which, they are dissolved. Some of the substances which have used for centuries to indicate the acidity or alkalinity of water, are still employed as acid/base indicators. Many plants or plant parts contain chemicals from the naturally coloured anthocyanin family of compounds. They are red in acidic and blue in basic solutions (Geroge et al. 1987). The dyes/pigments in plants are natural substances commonly used as acid-base indicators and are weak acids and bases (Geroge et al. 1987), (Ekandem and Owor, 1997) and (Okoye and Oforka, 2009). Indicators used in the laboratories are coloured organic dyes that gives different colours in acidic and basic media. Many indicators can be extracted from plants and some graden plants can be used as ph indicators, e.g. Napoleona Vogelii Hook (8 - 12) (Francis, et al. 1996), (Finar, 2004), (Fuleki, 1979), (Ageti et  al., 2005)and (Del et al., 2004).
            Napoleona Vogelii Hook (popularly known as “Udarutobo or Nkpodo”, among the Igbo speaking people) is one of the most potent species of lecythidaceae that is richly endowed with pigments. The fruits are green unripe, and reddish-orange ripe. (Francis, et al., 1966) defined it as “a genus of about 125 species of trees native to the tropical rainforest of Africa, and are classified in the family of lecythidaceae, and subfamily of Vogelii Hook. An ever-prickly leafy tree, growing about 2.50m to 5.0m tall, Napoleona Vogelii Hook is a sweet and edible fruitfound in holly – a tree with hard prickly leaves all through the year and the ripe fruits in the dry seasons. The trees are grown widly on a prickly rocky bush in most parts of Ebonyi state of Nigeria, particularly  along the Akpoha – Amasiri axes. The fruits are widely eaten by bush monkeys hence the local name “udautobo”, meaning monkey apple. Farmers and rural dwellers also eat the flesh of Napoleona Vogelii Hook fruits. The colourful skins also attract the attention of other animals, which may eat the fruits and disperse the seeds. Many researchers such as (Munoz-Espada et al., 2004), (Hosseinian and Beta, 2007), (Wada and Ou, 2002) and (Siriwoharn et al., 2004) have noted that the red coloration of the fruits may camouflage them from herbivores blind to red wavelengths, or signal un-palatability, since anthocyanin often coincides with unpalatable and phenolic compounds. Nature, primitive agriculture and plant breeding have produced various crops containing anthocyanins (Finar, 2004), (Fuleki, 1979), (Agati et al., 2005), (Del et al., 2004), (Munoz-Espada et al. 2004), (Hosseinian and Beta, 2007) and (Wada and Ou, 2002),  including Napoleona Vogelii Hook fruits, blue- or red-fleshed potatoes, and purple or red broccoli cabbage, bred conventionally for high anthocyanin content by crossing wild relatives with the common tomato to large and more palatable fruit (Agati et al., 2005) and (Del et al., 2004)

Aims and Objectives of the Research
            The purpose of this research was to investigate the Napoleona Vogelii Hook fruit pigments as a potential source of acid-base indicator.

Scope of the Research   
            The scope of this work is the limit to which I got to, in the actualization of my aim. Ranging from, extraction of the indicator from the three major phases thin layer chromatographic separation, titration of the extracts from each case and compassion with some standard indicators to as certain the level of accuracy and precision of the standard indicator.
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