INTRODUCTION
•Despite
all the advances in modern and orthodox medicine, herbal remedies still plays a
significant role in the lives of many people. In developing countries,
particularly Africa, Nigeria not an exception.
• A vast
majority of the population, particularly those living in the village depends
largely on the herbal remedies, Sofowora (1993)
asserted that 70% of the third world population diagnose, prevent or eliminate
diseases through the use of medicinal plants.
•
JUSTIFICATION
•To
the best of our
knowledge; there is no scientific basis / study for the ethno-pharmacological
use of Acacia
polyacantha to enhance sexual performance.
OBJECTIVES OF THE STUDY
• To
determine the effect of the plant extract on mounting frequency.
•To investigate the effect of the plant
extract on sperm count, sperm motility, and sperm morphology of Wistar rats.
•
MATERIALS AND METHODS
•50 Wistar rats of
both sexes
• Group A (control) is given distilled
water
•Groups
B, C, and D were administered graded doses of 150, 300, and 600 mg/kg
respectively of the aqueous methanolic stem
bark extract of acacia polyacantha orally for 14 days
•Group E were given standard drug sildenafil citrate
(viagra) 5mg/kg
1 hour prior to the commencement of the experiment
SAMPLE COLLECTION AND ANALYSIS
• The
method of (Subramoniam et
al., 1997,) was
used in mounting frequency.
•For semen characteristic the method of (Sinha et al,.2001) was adopted.
• Statistical analysis was done using
one way analysis of variance (ANOVA) Values of p<0.05 was considered
statistically significant.
•
CONCULSION
•Hence, in conclusion
the stem bark extract of Acacia polyacantha did not
significantly affect mounting frequency, sperm count, sperm motility in adult
rats. But however, it significantly raised the number of normal sperm morphology suggesting a modulatory effect of Acacia
polyacantha.
•
CONCULSION
•Hence, in conclusion
the stem bark extract of Acacia polyacantha did not
significantly affect mounting frequency, sperm count, sperm motility in adult
rats. But however, it significantly raised the number of normal sperm morphology suggesting a modulatory effect of Acacia
polyacantha.
•
REFERENCE
•Singh, R.
P., Dhanalakshmi, S., and
Rao, A. R.
(2000). Chemomodulatory action
of Aloe vera on the
profiles of enzymes associated with carcinogen metabolism and antioxidant
status regulation in mice. Phytomedicine;7(3):209-219.
•
•Subramoniam, A., Mdhavachandran, R., Rajasekharan, S. and
Push- pangadan, P.
(1997). Aphrodisiac property of trichopus eylanicus extract in male mice.J Ethnopharmacol 57:
21-21.
•Sofowora, A.
(1993). Medicinal plants and traditional medicine in Africa. (2nd edition)
spectrum Books. Ltd Ibadan. Pp :145 -152
BY
USMAN ADAMA WAWATA (A.B.U.)
PRO.A.A.U.DIKKO (B.U.K)
DR.K.V.OLURUNSHOLA(A.B.U.).